Follow
Jay Dela Cruz, Ph.D.
Jay Dela Cruz, Ph.D.
InTouch BioSolutions LLC
Verified email at intouchbio.com
Title
Cited by
Cited by
Year
Recombinant anti-human HER2/neu IgG3-(GM-CSF) fusion protein retains antigen specificity and cytokine function and demonstrates antitumor activity
JS Dela Cruz, KR Trinh, SL Morrison, ML Penichet
The Journal of Immunology 165 (9), 5112-5121, 2000
1062000
An anti-transferrin receptor-avidin fusion protein exhibits both strong proapoptotic activity and the ability to deliver various molecules into cancer cells
PP Ng, JS Dela Cruz, DN Sorour, JM Stinebaugh, SU Shin, DS Shin, ...
Proceedings of the National Academy of Sciences 99 (16), 10706-10711, 2002
1022002
Protein vaccination with the HER2/neu extracellular domain plus anti-HER2/neu antibody–cytokine fusion proteins induces a protective anti-HER2/neu immune response in mice
JS Dela Cruz, SY Lau, EM Ramirez, C De Giovanni, G Forni, SL Morrison, ...
Vaccine 21 (13-14), 1317-1326, 2003
922003
Antibody-cytokine fusion proteins: innovative weapons in the war against cancer
JS Dela Cruz, TH Huang, ML Penichet, SL Morrison
Clinical and experimental medicine 4 (2), 57-64, 2004
762004
A recombinant IgG3-(IL-2) fusion protein for the treatment of human HER2/neu expressing tumors
ML Penichet, JS Dela Cruz, SU Shin, SL Morrison
Human antibodies 10 (1), 43-49, 2001
672001
Vaccination with novel combinations of anti-HER2/neu cytokines fusion proteins and soluble protein antigen elicits a protective immune response against HER2/neu expressing tumors
G Helguera, JS Dela Cruz, C Lowe, PP Ng, R Trinh, SL Morrison, ...
Vaccine 24 (3), 304-316, 2006
402006
Insights into the mechanism of anti-tumor immunity in mice vaccinated with the human HER2/neu extracellular domain plus anti-HER2/neu IgG3-(IL-2) or anti-HER2/neu IgG3-(GM-CSF …
JS Dela Cruz, SL Morrison, ML Penichet
Vaccine 23 (39), 4793-4803, 2005
352005
Antibody fusion proteins: effective adjuvants of protein vaccination
ML Penichet, JS Dela Cruz, L Peng, SL Morrison
US Patent 7,736,652, 2010
312010
Mechanism of antitumor activity of a single-chain interleukin-12 IgG3 antibody fusion protein (mscIL-12. her2. IgG3)
LS Peng, ML Penichet, JS Dela Cruz, SL Sampogna, SL Morrison
Journal of Interferon & Cytokine Research 21 (9), 709-720, 2001
312001
Anti-HER2/neu IgG3–(IL-2) and anti-HER2/neu IgG3–(GM-CSF) promote HER2/neu processing and presentation by dendritic cells: Implications in immunotherapy and vaccination strategies
JS Dela Cruz, KR Trinh, HW Chen, A Ribas, SL Morrison, ML Penichet
Molecular immunology 43 (6), 667-676, 2006
272006
A murine B cell lymphoma expressing human HER2/neu undergoes spontaneous tumor regression and elicits antitumor immunity
ML Penichet, JS Dela Cruz, PM Challita-Eid, JD Rosenblatt, SL Morrison
Cancer Immunology, Immunotherapy 49 (12), 649-662, 2001
92001
Protein M fusion proteins and uses
J Dela Cruz
https://patents.google.com/patent/US11401309B2/en, 2022
2022
New insights underlying the early events of dopaminergic dysfunction in Parkinson’s Disease
HL Dela Cruz, EL Dela Cruz, CJ Zurhellen, HT York, JA Baun, ...
bioRxiv, 2020.09. 27.313957, 2020
2020
TREATMENT OF SYNUCLEINOPATHY AND ANIMAL MODELS OF SYNUCLEINOPATHY
JS Dela Cruz
https://patents.google.com/patent/US20220135968A1/en, 2019
2019
Development of PKC Theta-Specific Inhibitors to Modulate T-Cell Activation (B35)
F Karim, A Baruch, J Dela Cruz, D Maclean, K Das, S Harrision
The Journal of Immunology 178 (1 Supplement), LB7-LB7, 2007
2007
Mechanism of apoptosis induced by an IgG3-avidin fusion protein specific for the human transferrin receptor
PP Ng, SZ Lomas, JS Dela Cruz, G Helguera, B Bonavida, SL Morrison, ...
Cancer Research 65 (9 Supplement), 531-531, 2005
2005
Combinations of cytokines fused to antibodies to enhance the immune response against HER2/neu expressing tumors
GF Helguera, JS Dela Cruz, C Lowe, PP Ng, R Trinh, SL Morrison, ...
Cancer Research 65 (9 Supplement), 166-167, 2005
2005
Characterization of two bi-functional anti-HER2/neu IgG3-cytokine fusion proteins with potential use as cancer therapeutics
GF Helguera, VR Kyinn, C Lowe, JS Dela Cruz, R Trinh, PP Ng, ...
Cancer Research 64 (7 Supplement), 1078-1078, 2004
2004
Anti-HER2/neu IgG3-(IL-2) efficiently redirects HER2/neu antigen processing in dendritic cells resulting in effective antigen presentation and tumor protection.
JS Dela Cruz, HW Chen, RK Trinh, S Narasimhan, WP Naing, A Ribas, ...
Cancer Research 64 (7 Supplement), 495-496, 2004
2004
Anti-HER2/neu IgG3-(IL-2) and anti-HER2/neu IgG3-(GM-CSF) antibody fusion proteins are potent adjuvants of HER2/neu vaccination: Characterization of a HER2/neu specific anti …
JS Dela Cruz
University of California, Los Angeles, 2004
2004
The system can't perform the operation now. Try again later.
Articles 1–20