| Mutant IDH inhibits IFNγ–TET2 signaling to promote immunoevasion and tumor maintenance in cholangiocarcinoma MJ Wu, L Shi, J Dubrot, J Merritt, V Vijay, TY Wei, E Kessler, KE Olander, ... Cancer discovery 12 (3), 812-835, 2022 | 57 | 2022 |
| Functionally distinct roles for TET-oxidized 5-methylcytosine bases in somatic reprogramming to pluripotency BA Caldwell, MY Liu, RD Prasasya, T Wang, JE DeNizio, NA Leu, ... Molecular cell 81 (4), 859-869. e8, 2021 | 40 | 2021 |
| Controllable genome editing with split-engineered base editors KN Berríos, NH Evitt, RA DeWeerd, D Ren, M Luo, A Barka, T Wang, ... Nature Chemical Biology 17 (12), 1262-1270, 2021 | 34 | 2021 |
| Consequences of Periodic α-to-β3 Residue Replacement for Immunological Recognition of Peptide Epitopes RW Cheloha, JA Sullivan, T Wang, JM Sand, J Sidney, A Sette, ME Cook, ... ACS chemical biology 10 (3), 844-854, 2015 | 29 | 2015 |
| Enzymatic approaches for profiling cytosine methylation and hydroxymethylation T Wang, CE Loo, RM Kohli Molecular Metabolism 57, 101314, 2022 | 15 | 2022 |
| The base-editing enzyme APOBEC3A catalyzes cytosine deamination in RNA with low proficiency and high selectivity A Barka, KN Berríos, P Bailer, EK Schutsky, T Wang, RM Kohli ACS chemical biology 17 (3), 629-636, 2022 | 14 | 2022 |
| Nucleobase Modifiers Identify TET Enzymes as Bifunctional DNA Dioxygenases Capable of Direct N‐Demethylation U Ghanty, T Wang, RM Kohli Angewandte Chemie International Edition 59 (28), 11312-11315, 2020 | 14 | 2020 |
| Direct enzymatic sequencing of 5-methylcytosine at single-base resolution T Wang, JM Fowler, L Liu, CE Loo, M Luo, EK Schutsky, KN Berríos, ... Nature chemical biology 19 (8), 1004-1012, 2023 | 10 | 2023 |
| Joint single-cell profiling resolves 5mC and 5hmC and reveals their distinct gene regulatory effects EB Fabyanic, P Hu, Q Qiu, KN Berríos, DR Connolly, T Wang, J Flournoy, ... Nature Biotechnology, 1-15, 2023 | 9 | 2023 |
| Bisulfite-free sequencing of 5-hydroxymethylcytosine with APOBEC-coupled epigenetic sequencing (ACE-Seq) T Wang, M Luo, KN Berrios, EK Schutsky, H Wu, RM Kohli DNA Modifications: Methods and Protocols, 349-367, 2021 | 8 | 2021 |
| Recognition of class II MHC peptide ligands that contain β-amino acids RW Cheloha, AW Woodham, D Bousbaine, T Wang, S Liu, J Sidney, ... The Journal of Immunology 203 (6), 1619-1628, 2019 | 8 | 2019 |
| Quantitative single cell 5hmC sequencing reveals non-canonical gene regulation by non-CG hydroxymethylation EB Fabyanic, P Hu, Q Qiu, T Wang, KN Berríos, J Flournoy, DR Connolly, ... bioRxiv, 2021.03. 23.434325, 2021 | 7 | 2021 |
| Discovery of an unnatural DNA modification derived from a natural secondary metabolite T Wang, RM Kohli Cell chemical biology 28 (1), 97-104. e4, 2021 | 6 | 2021 |
| Consequences of Periodic α-to-β3 Residue Replacement for Immunological Recognition of Peptide Epitopes, ACS Chem RW Cheloha, JA Sullivan, T Wang, JM Sand, J Sidney, A Sette, ME Cook, ... Biol 10 (3), 844-854, 2015 | 5 | 2015 |
| Revealing Drivers for Carboxy-S-adenosyl-l-methionine Use by Neomorphic Variants of a DNA Methyltransferase CE Loo, MA Hix, T Wang, GA Cisneros, RM Kohli ACS Chemical Biology 18 (10), 2224-2232, 2023 | | 2023 |
| Modified adapters for enzymatic dna deamination and methods of use thereof for epigenetic sequencing of free and immobilized dna C Loo, T Wang, R Kohli WO Patent App. WO2023288222A1, 2023 | | 2023 |
| Compositions and Methods for DNA Cytosine Carboxymethylation T Wang, EK Schutsky, RM Kohli WO Patent App. WO2021236778A3, 2021 | | 2021 |
| Discovery and Application of Cytosine Carboxymethylation T Wang University of Pennsylvania, 2021 | | 2021 |
| Evaluation of antibody recognition limitations induced by systematic backbone homologation of peptidic antigens T Wang, RW Cheloha, JM Sand, ME Cook, SH Gellman ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 247, 2014 | | 2014 |
Hao WuAssociate Professor, Department of Genetics & Penn Epigenetics Institute, University of PennsylvaniaVerified email at upenn.edu
