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Alexandre Amlie-Wolf
Alexandre Amlie-Wolf
Computational Biologist, Arrakis Therapeutics
Verified email at arrakistx.com - Homepage
Title
Cited by
Cited by
Year
Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ...
Nature genetics 51 (3), 414-430, 2019
21302019
Dysregulation of the epigenetic landscape of normal aging in Alzheimer’s disease
R Nativio, G Donahue, A Berson, Y Lan, A Amlie-Wolf, F Tuzer, JB Toledo, ...
Nature neuroscience 21 (4), 497-505, 2018
2602018
An integrated multi-omics approach identifies epigenetic alterations associated with Alzheimer’s disease
R Nativio, Y Lan, G Donahue, S Sidoli, A Berson, AR Srinivasan, ...
Nature genetics 52 (10), 1024-1035, 2020
2172020
Loss of Nuclear TDP-43 Is Associated with Decondensation of LINE Retrotransposons
EY Liu, J Russ, CP Cali, JM Phan, A Amlie-Wolf, EB Lee
Cell reports 27 (5), 1409-1421. e6, 2019
1532019
DASHR: database of small human noncoding RNAs
YY Leung, PP Kuksa, A Amlie-Wolf, O Valladares, LH Ungar, S Kannan, ...
Nucleic acids research 44 (D1), D216-D222, 2016
842016
Alzheimer Disease Genetics Consortium (ADGC) European Alzheimer’s Disease Initiative (EADI) Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE …
BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ...
Nat Genet 51 (3), 414-430, 2019
742019
Transcriptomic changes due to cytoplasmic TDP-43 expression reveal dysregulation of histone transcripts and nuclear chromatin
A Amlie-Wolf, P Ryvkin, R Tong, I Dragomir, ER Suh, Y Xu, ...
PLoS One 10 (10), e0141836, 2015
642015
INFERNO: inferring the molecular mechanisms of noncoding genetic variants
A Amlie-Wolf, M Tang, EE Mlynarski, PP Kuksa, O Valladares, Z Katanic, ...
Nucleic Acids Research, 2018
542018
DASHR 2.0: integrated database of human small non-coding RNA genes and mature products
PP Kuksa, A Amlie-Wolf, Z Katanic, O Valladares, LS Wang, YY Leung
Bioinformatics 1, 7, 2018
532018
Inferring the molecular mechanisms of noncoding Alzheimer’s disease-associated genetic variants
A Amlie-Wolf, M Tang, J Way, B Dombroski, M Jiang, N Vrettos, YF Chou, ...
Journal of Alzheimer's Disease 72 (1), 301-318, 2019
272019
Activity of the poly (A) binding protein MSUT2 determines susceptibility to pathological tau in the mammalian brain
JM Wheeler, P McMillan, TJ Strovas, NF Liachko, A Amlie-Wolf, RL Kow, ...
Science translational medicine 11 (523), eaao6545, 2019
262019
SPAR: small RNA-seq portal for analysis of sequencing experiments
PP Kuksa, A Amlie-Wolf, Ž Katanić, O Valladares, LS Wang, YY Leung
Nucleic acids research 46 (W1), W36-W42, 2018
222018
SparkINFERNO: a scalable high-throughput pipeline for inferring molecular mechanisms of non-coding genetic variants
PP Kuksa, CY Lee, A Amlie-Wolf, P Gangadharan, EE Mlynarski, YF Chou, ...
Bioinformatics 36 (12), 3879-3881, 2020
72020
FILER: a framework for harmonizing and querying large-scale functional genomics knowledge
PP Kuksa, YY Leung, P Gangadharan, Z Katanic, L Kleidermacher, ...
NAR genomics and bioinformatics 4 (1), lqab123, 2022
52022
HIPPIE2: a method for fine-scale identification of physically interacting chromatin regions
PP Kuksa, A Amlie-Wolf, YC Hwang, O Valladares, BD Gregory, LS Wang
NAR genomics and bioinformatics 2 (2), lqaa022, 2020
42020
Using INFERNO to Infer the Molecular Mechanisms Underlying Noncoding Genetic Associations
A Amlie-Wolf, PP Kuksa, CY Lee, E Mlynarski, YY Leung, LS Wang
Functional Analysis of Long Non-Coding RNAs, 73-91, 2021
22021
FILER: large-scale, harmonized FunctIonaL gEnomics Repository
PP Kuksa, P Gangadharan, Z Katanic, L Kleidermacher, A Amlie-Wolf, ...
bioRxiv, 2021
12021
Genome‐wide profiling of the noncoding regulatory mechanisms in Alzheimer’s disease: Genetics/genetic factors of Alzheimer's disease
L Kleidermacher, P Kuksa, CY Lee, A Amlie‐Wolf, GD Schellenberg, ...
Alzheimer's & Dementia 16, e044268, 2020
2020
Genome-wide profiling of the noncoding regulatory mechanisms in Alzheimer’s Disease
L Kleidermacher, P Kuksa, CY Lee, A Amlie-Wolf, GD Schellenberg, ...
2020 Alzheimer's Association International Conference, 2020
2020
P3‐122: INFERRING THE NONCODING REGULATORY MECHANISMS UNDERLYING GENETIC SUSCEPTIBILITY CONTRIBUTED BY DIFFERENT CSF ENDOPHENOTYPES IN AD
YY Leung, A Amlie-Wolf, LS Wang, GD Schellenberg
Alzheimer's & Dementia 15, P977-P977, 2019
2019
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