Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions DM Howard, MJ Adams, TK Clarke, JD Hafferty, J Gibson, M Shirali, ... Nature neuroscience 22 (3), 343-352, 2019 | 2086 | 2019 |
Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways DM Howard, MJ Adams, M Shirali, TK Clarke, RE Marioni, G Davies, ... Nature communications 9 (1), 1470, 2018 | 568 | 2018 |
Major depressive disorder working group of the psychiatric genomics consortium DM Howard, MJ Adams, WD Hill, TK Clarke, MJ Adams, TK Clarke, ... Nat. Commun 11, 230, 2020 | 221 | 2020 |
Association of polygenic risk for major psychiatric illness with subcortical volumes and white matter integrity in UK Biobank LM Reus, X Shen, J Gibson, E Wigmore, L Ligthart, MJ Adams, G Davies, ... Scientific reports 7 (1), 42140, 2017 | 100 | 2017 |
Genetic and environmental risk for chronic pain and the contribution of risk variants for major depressive disorder: a family-based mixed-model analysis AM McIntosh, LS Hall, Y Zeng, MJ Adams, J Gibson, E Wigmore, ... PLoS medicine 13 (8), e1002090, 2016 | 93 | 2016 |
Genome-wide meta-analyses of stratified depression in Generation Scotland and UK Biobank LS Hall, MJ Adams, A Arnau-Soler, TK Clarke, DM Howard, Y Zeng, ... Translational psychiatry 8 (1), 9, 2018 | 79 | 2018 |
Impact of polygenic risk for schizophrenia on cortical structure in UK Biobank E Neilson, X Shen, SR Cox, TK Clarke, EM Wigmore, J Gibson, ... Biological Psychiatry 86 (7), 536-544, 2019 | 69 | 2019 |
Genome-wide association study of antidepressant treatment resistance in a population-based cohort using health service prescription data and meta-analysis with GENDEP EM Wigmore, JD Hafferty, LS Hall, DM Howard, TK Clarke, C Fabbri, ... The pharmacogenomics journal 20 (2), 329-341, 2020 | 65 | 2020 |
Identifying the common genetic basis of antidepressant response O Pain, K Hodgson, V Trubetskoy, S Ripke, VS Marshe, MJ Adams, ... Biological psychiatry global open science 2 (2), 115-126, 2022 | 61 | 2022 |
Assessing the presence of shared genetic architecture between Alzheimer’s disease and major depressive disorder using genome-wide association data J Gibson, TC Russ, MJ Adams, TK Clarke, DM Howard, LS Hall, ... Translational psychiatry 7 (4), e1094-e1094, 2017 | 52 | 2017 |
Identification of a missense variant in SPDL1 associated with idiopathic pulmonary fibrosis RS Dhindsa, J Mattsson, A Nag, Q Wang, LV Wain, R Allen, EM Wigmore, ... Communications biology 4 (1), 392, 2021 | 50 | 2021 |
Do regional brain volumes and major depressive disorder share genetic architecture? A study of Generation Scotland (n= 19 762), UK Biobank (n= 24 048) and the English … EM Wigmore, TK Clarke, DM Howard, MJ Adams, LS Hall, Y Zeng, ... Translational psychiatry 7 (8), e1205-e1205, 2017 | 37 | 2017 |
Dissection of major depressive disorder using polygenic risk scores for schizophrenia in two independent cohorts HC Whalley, MJ Adams, LS Hall, TK Clarke, AM Fernandez-Pujals, ... Translational psychiatry 6 (11), e938-e938, 2016 | 34 | 2016 |
andMe Research T DM Howard, MJ Adams, TK Clarke, JD Hafferty, J Gibson, M Shirali, ... Major Depressive Disorder Working Group of the Psychiatric Genomics C …, 2019 | 31 | 2019 |
Pharmaco-epidemiology of antidepressant exposure in a UK cohort record-linkage study JD Hafferty, EM Wigmore, DM Howard, MJ Adams, TK Clarke, ... Journal of Psychopharmacology 33 (4), 482-493, 2019 | 25 | 2019 |
Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Trzaskowski M, Byrne EM, Ripke S, Smith DJ, Sullivan PF, Wray NR, Breen G, Lewis CM, McIntosh AM … DM Howard, MJ Adams, TK Clarke, JD Hafferty, J Gibson, M Shirali, ... Nature Neuroscience 22 (3), 343-352, 0 | 22 | |
Genome-wide meta-analysis of depression in 807,553 individuals identifies 102 independent variants with replication in a further 1,507,153 individuals DM Howard, MJ Adams, TK Clarke, JD Hafferty, J Gibson, M Shirali, ... BioRxiv 6288, 433367, 2018 | 16 | 2018 |
Antidepressant response in major depressive disorder: a genome-wide association study O Pain, K Hodgson, V Trubetskoy, S Ripke, VS Marshe, MJ Adams, ... MedRxiv, 2020.12. 11.20245035, 2020 | 15 | 2020 |
Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways (vol 9, 1470, 2018) DM Howard, MJ Adams, M Shirali, TK Clarke, RE Marioni, G Davies, ... NATURE COMMUNICATIONS 12 (1), 2021 | 14 | 2021 |
Combining the AKT inhibitor capivasertib and SERD fulvestrant is effective in palbociclib-resistant ER+ breast cancer preclinical models L Hopcroft, EM Wigmore, SC Williamson, S Ros, C Eberlein, JI Moss, ... NPJ Breast Cancer 9 (1), 64, 2023 | 12 | 2023 |