|Leveraging polygenic functional enrichment to improve GWAS power|
G Kichaev, G Bhatia, PR Loh, S Gazal, K Burch, MK Freund, A Schoech, ...
The American Journal of Human Genetics 104 (1), 65-75, 2019
|Accurate estimation of SNP-heritability from biobank-scale data irrespective of genetic architecture|
K Hou, KS Burch, A Majumdar, H Shi, N Mancuso, Y Wu, S Sankararaman, ...
Nature Genetics 51 (8), 1244-1251, 2019
|Phenotype-Specific Enrichment of Mendelian Disorder Genes near GWAS Regions across 62 Complex Traits|
MK Freund, KS Burch, H Shi, N Mancuso, G Kichaev, KM Garske, DZ Pan, ...
The American Journal of Human Genetics 103 (4), 535-552, 2018
|Localizing Components of Shared Transethnic Genetic Architecture of Complex Traits from GWAS Summary Data|
H Shi, KS Burch, R Johnson, MK Freund, G Kichaev, N Mancuso, ...
The American Journal of Human Genetics 106 (6), 805-817, 2020
|Efficient variance components analysis across millions of genomes|
A Pazokitoroudi, Y Wu, KS Burch, K Hou, B Pasaniuc, S Sankararaman
Nature Communications 11, 4020, 2020
|Large uncertainty in individual polygenic risk score estimation impacts PRS-based risk stratification|
Y Ding, K Hou, KS Burch, S Lapinska, F Privé, B Vilhjálmsson, ...
Nature genetics 54 (1), 30-39, 2022
|Quantifying the contribution of dominance deviation effects to complex trait variation in biobank-scale data|
A Pazokitoroudi, AM Chiu, KS Burch, B Pasaniuc, S Sankararaman
The American Journal of Human Genetics 108 (5), 799-808, 2021
|Integrative analysis of Dupuytren's disease identifies novel risk locus and reveals a shared genetic etiology with BMI|
M Major, MK Freund, KS Burch, N Mancuso, M Ng, D Furniss, B Pasaniuc, ...
Genetic epidemiology, 2019
|Leveraging genomic diversity for discovery in an electronic health record linked biobank: the UCLA ATLAS Community Health Initiative|
R Johnson, Y Ding, V Venkateswaran, A Bhattacharya, K Boulier, A Chiu, ...
Genome medicine 14 (1), 1-23, 2022
|On powerful GWAS in admixed populations|
K Hou, A Bhattacharya, R Mester, KS Burch, B Pasaniuc
Nature genetics 53 (12), 1631-1633, 2021
|Estimation of regional polygenicity from GWAS provides insights into the genetic architecture of complex traits|
R Johnson, KS Burch, K Hou, M Paciuc, B Pasaniuc, S Sankararaman
PLOS Computational Biology 17 (10), e1009483, 2021
|Fast estimation of genetic correlation for Biobank-scale data|
Y Wu, KS Burch, A Ganna, P Pajukanta, B Pasaniuc, S Sankararaman
The American Journal of Human Genetics, 2021
|A two-step approach to testing overall effect of gene-environment interaction for multiple phenotypes|
A Majumdar, KS Burch, S Sankararaman, B Pasaniuc, WJ Gauderman, ...
Bioinformatics 36 (24), 5640–5648, 2020
|Partitioning gene-level contributions to complex-trait heritability by allele frequency identifies disease-relevant genes|
KS Burch, K Hou, Y Ding, Y Wang, S Gazal, H Shi, B Pasaniuc
The American Journal of Human Genetics 109 (4), 692-709, 2022
|Nausea and Vomiting of Pregnancy and HG Risk Genes Associated With Blood Levels, Sleep, Stomach Pain, and Other Traits [23N]|
MS Fejzo, K Burch, P Mullin, KW MacGibbon, B Pasaniuc
Obstetrics & Gynecology 135, 151S-152S, 2020
|Methods for the Quantitative Characterization of the Genetic Basis of Human Complex Traits|