Targeting RNA with small-molecule drugs: therapeutic promise and chemical challenges J Gallego, G Varani Accounts of chemical research 34 (10), 836-843, 2001 | 382 | 2001 |
A conserved RNA structure within the HCV IRES eIF3-binding site AJ Collier, J Gallego, R Klinck, PT Cole, SJ Harris, GP Harrison, ... Nature structural biology 9 (5), 375-380, 2002 | 144 | 2002 |
Secondary structure determination of conserved SARS-CoV-2 RNA elements by NMR spectroscopy A Wacker, JE Weigand, SR Akabayov, N Altincekic, JK Bains, ... Nucleic acids research 48 (22), 12415-12435, 2020 | 134 | 2020 |
Evolving a polymerase for hydrophobic base analogues D Loakes, J Gallego, VB Pinheiro, ET Kool, P Holliger Journal of the American Chemical Society 131 (41), 14827-14837, 2009 | 97 | 2009 |
Centromeric pyrimidine strands fold into an intercalated motif by forming a double hairpin with a novel T: G: G: T tetrad: solution structure of the d (TCCCGTTTCCA) dimer J Gallego, SH Chou, BR Reid Journal of molecular biology 273 (4), 840-856, 1997 | 95 | 1997 |
Three-way RNA junctions with remote tertiary contacts: a recurrent and highly versatile fold M de la Peña, D Dufour, J Gallego Rna 15 (11), 1949-1964, 2009 | 82 | 2009 |
The PUA domain− a structural and functional overview I Pérez‐Arellano, J Gallego, J Cervera The FEBS journal 274 (19), 4972-4984, 2007 | 80 | 2007 |
Solution structure and dynamics of a complex between DNA and the antitumor bisnaphthalimide LU-79553: intercalated ring flipping on the millisecond time scale J Gallego, BR Reid Biochemistry 38 (46), 15104-15115, 1999 | 80 | 1999 |
Structure and stability of wild-type and mutant RNA internal loops from the SL-1 domain of the HIV-1 packaging signal J Greatorex, J Gallego, G Varani, A Lever Journal of molecular biology 322 (3), 543-557, 2002 | 72 | 2002 |
Structure–function analysis of the ribozymes of chrysanthemum chlorotic mottle viroid: a loop–loop interaction motif conserved in most natural hammerheads D Dufour, M de la Pena, S Gago, R Flores, J Gallego Nucleic acids research 37 (2), 368-381, 2009 | 63 | 2009 |
Structure–affinity relationships for the binding of actinomycin D to DNA J Gallego, AR Ortiz, B de Pascual-Teresa, F Gago Journal of computer-aided molecular design 11, 114-128, 1997 | 55 | 1997 |
The hepatitis C virus internal ribosome-entry site: a new target for antiviral research J Gallego, G Varani Biochemical Society Transactions 30 (2), 140-145, 2002 | 53 | 2002 |
A molecular dynamics study of the bis-intercalation complexes of echinomycin with d (ACGT) 2 and d (TCGA) 2: rationale for sequence-specific Hoogsteen base pairing J Gallego, AR Ortiz, F Gago Journal of medicinal chemistry 36 (11), 1548-1561, 1993 | 49 | 1993 |
The folding of centromeric DNA strands into intercalated structures: a physicochemical and computational study J Gallego, EB Golden, DE Stanley, BR Reid Journal of molecular biology 285 (3), 1039-1052, 1999 | 45 | 1999 |
Structure and functional relevance of a transcription-regulating sequence involved in coronavirus discontinuous RNA synthesis D Dufour, PA Mateos-Gomez, L Enjuanes, J Gallego, I Sola Journal of virology 85 (10), 4963-4973, 2011 | 44 | 2011 |
DNA sequence-specific reading by echinomycin: role of hydrogen bonding and stacking interactions J Gallego, FJ Luque, M Orozco, C Burgos, J Alvarez-Builla, MM Rodrigo, ... Journal of medicinal chemistry 37 (11), 1602-1609, 1994 | 43 | 1994 |
Rev binds specifically to a purine loop in the SL1 region of the HIV-1 leader RNA J Gallego, J Greatorex, H Zhang, B Yang, S Arunachalam, J Fang, ... Journal of Biological Chemistry 278 (41), 40385-40391, 2003 | 41 | 2003 |
Implications of a consensus recognition site for phosphatidylcholine separate from the active site in cobra venom phospholipases A2 AR Ortiz, MT Pisabarro, J Gallego, F Gago Biochemistry 31 (11), 2887-2896, 1992 | 41 | 1992 |
Indirect effects modulating the interaction between DNA and a cytotoxic bisnaphthalimide reveal a two-step binding process L González-Bulnes, J Gallego Journal of the American Chemical Society 131 (22), 7781-7791, 2009 | 36 | 2009 |
Structure‐Based Design of an RNA‐Binding p‐Terphenylene Scaffold that Inhibits HIV‐1 Rev Protein Function L González‐Bulnes, I Ibáñez, LM Bedoya, M Beltrán, S Catalán, J Alcamí, ... Angewandte Chemie International Edition 52 (50), 13405-13409, 2013 | 35 | 2013 |