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Chao Chen
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A new antibiotic kills pathogens without detectable resistance
LL Ling, T Schneider, AJ Peoples, AL Spoering, I Engels, BP Conlon, ...
Nature 517 (7535), 455-459, 2015
23792015
The association between sterilizing activity and drug distribution into tuberculosis lesions
CEBVD Brendan Prideaux, Laura E Via, Matthew D Zimmerman, Seokyong Eum ...
Nature Medicine, 2015
3942015
Immune activation of the host cell induces drug tolerance in Mycobacterium tuberculosis both in vitro and in vivo
Y Liu, S Tan, L Huang, RB Abramovitch, KH Rohde, MD Zimmerman, ...
Journal of Experimental Medicine 213 (5), 809-825, 2016
1382016
Bedaquiline and Pyrazinamide Treatment Responses Are Affected by Pulmonary Lesion Heterogeneity in Mycobacterium tuberculosis Infected C3HeB/FeJ Mice
SM Irwin, B Prideaux, ER Lyon, MD Zimmerman, EJ Brooks, CA Schrupp, ...
ACS infectious diseases 2 (4), 251-267, 2016
932016
Verapamil targets membrane energetics in Mycobacterium tuberculosis
C Chen, S Gardete, RS Jansen, A Shetty, T Dick, KY Rhee, V Dartois
Antimicrobial agents and chemotherapy 62 (5), e02107-17, 2018
812018
Ethambutol partitioning in tuberculous pulmonary lesions explains its clinical efficacy
M Zimmerman, J Lestner, B Prideaux, P O'Brien, I Dias-Freedman, ...
Antimicrobial agents and chemotherapy 61 (9), e00924-17, 2017
612017
Identification of new MmpL3 inhibitors by untargeted and targeted mutant screens defines MmpL3 domains with differential resistance
JT Williams, ER Haiderer, GB Coulson, KN Conner, E Ellsworth, C Chen, ...
Antimicrobial agents and chemotherapy 63 (10), e00547-19, 2019
292019
Diarylacylhydrazones: Clostridium-selective antibacterials with activity against stationary-phase cells
C Chen, NK Dolla, G Casadei, JB Bremner, K Lewis, MJ Kelso
Bioorganic & medicinal chemistry letters 24 (2), 595-600, 2014
222014
On the mechanism of berberine–INF55 (5-nitro-2-phenylindole) hybrid antibacterials
NK Dolla, C Chen, J Larkins-Ford, R Rajamuthiah, S Jagadeesan, ...
Australian journal of chemistry 67 (10), 1471-1480, 2014
192014
In Vitro and In Vivo Activities of HPi1, a Selective Antimicrobial against Helicobacter pylori
E Gavrish, B Shrestha, C Chen, I Lister, EJ North, L Yang, RE Lee, A Han, ...
Antimicrobial agents and chemotherapy 58 (6), 3255-3260, 2014
112014
Piperidine-4-carboxamides target DNA gyrase in Mycobacterium abscessus
DA Negatu, A Beuchel, A Madani, N Alvarez, C Chen, WW Aragaw, ...
Antimicrobial agents and chemotherapy 65 (8), e00676-21, 2021
72021
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