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Yufeng Xiao
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Year
Discovery of histone deacetylase 3 (HDAC3)-specific PROTACs
Y Xiao, J Wang, LY Zhao, X Chen, G Zheng, X Zhang, D Liao
Chemical Communications 56 (68), 9866-9869, 2020
782020
Piperlongumine (PL) conjugates induce targeted protein degradation
J Pei, Y Xiao, X Liu, W Hu, A Sobh, Y Yuan, S Zhou, N Hua, ...
Cell Chemical Biology 30 (2), 203-213, 2023
35*2023
Phosphodiesters as GPR84 antagonists for the treatment of ulcerative colitis
LH Chen, Q Zhang, YF Xiao, YC Fang, X Xie, FJ Nan
Journal of Medicinal Chemistry 65 (5), 3991-4006, 2022
162022
Sulfuretin protects hepatic cells through regulation of ROS levels and autophagic flux
Y Lu, Y Xiao, Y Li, J Li, F Nan, J Li
Acta Pharmacologica Sinica 40 (7), 908-918, 2019
162019
Recent advances in small molecular modulators targeting histone deacetylase 6
Y Xiao, X Zhang
Future Drug Discovery 2 (4), FDD53, 2020
152020
HDAC3 and HDAC8 PROTAC dual degrader reveals roles of histone acetylation in gene regulation
Y Xiao, S Hale, N Awasthee, C Meng, X Zhang, Y Liu, H Ding, Z Huo, D Lv, ...
Cell Chemical Biology, 2023
3*2023
Targeting intracellular proteins with cell type-specific functions for cancer immunotherapy
ME Carelock, RP Master, MC Kim, Z Jin, L Wang, CK Maharjan, N Hua, ...
Life Medicine 2 (3), lnad019, 2023
32023
Discovery of hydrazide-based HDAC8 selective PROTACs
Y Xiao, Y Liu, N Awasthee, C Meng, M He, S Hale, R Karki, Z Lin, R Kridel, ...
Cancer Research 84 (6_Supplement), 3236-3236, 2024
2024
PROTAC-mediated NR4A1 degradation as a novel strategy for cancer immunotherapy
L Wang, Y Xiao, Y Luo, RP Master, J Mo, MC Kim, Y Liu, CK Maharjan, ...
Journal of Experimental Medicine 221 (3), e20231519, 2024
2024
Unleashing the Power of NR4A1 Degradation as a Novel Strategy for Cancer Immunotherapy
L Wang, Y Xiao, Y Luo, RP Master, J Mo, MC Kim, Y Liu, UM Patel, X Li, ...
bioRxiv, 2023
2023
DISCOVERY OF PIPERLONGUMINE AS A NOVEL E3 LIGASE LIGAND
WH Daohong Zhou, Guangrong Zheng, Yaxia Yuan, Yufeng Xiao, Dongwen Lv, Jing ...
WO Patent WO2023114455A1, 2023
2023
Benzoylhydrazide-derived hdac degraders as therapeutics for treating cancer and other human diseases
D Liao, X Yufeng, X Zhang, G Zheng
US Patent US2023181746A1, 2023
2023
Proteolysis-targeting chimera against NR4A1 for cancer immunotherapy
L Wang, Y Xiao, R Master, Y Luo, G Zheng, D Zhou, W Zhang
The Journal of Immunology 210 (1_Supplement), 245.07-245.07, 2023
2023
Abstract LB002: Extracellular vesicle loading of proteolysis targeting chimeras for targeted therapeutic delivery
N Erwin, X Pan, N Awasthee, Y Xiao, G Zheng, D Liao, M He
Cancer Research 83 (8_Supplement), LB002-LB002, 2023
2023
Developing a PROTAC-based NR4A1 degrader for melanoma cancer therapy
R Master, Y Luo, Y Xiao, D Zhou, L Wang, G Zheng, W Zhang
Cancer Research 83 (7_Supplement), 4451-4451, 2023
2023
MODULATORS OF NUCLEAR RECEPTOR SUBFAMILY 4 GROUP A MEMBER 1 (NR4A1) AND USES THEREOF
W Zhang, G Zheng, D Zhou, Y Xiao, L Wang
WO Patent WO2022072094A2, 2022
2022
GPR84 receptor antagonist and use thereof
F Nan, X Xie, C Linhai, Q Zhang, X Yufeng, H Yang
US Patent 11,098,071, 2021
2021
Application of biphenyl phosphate compound as GPR84 antagonist
F Nan, X Xie, Y Xiao, Q Zhang, L Chen
CN Patent CN110,680,823 B, 2020
2020
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