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Michael W Pickup
Michael W Pickup
Stemcentrx
Verified email at abbvie.com
Title
Cited by
Cited by
Year
The extracellular matrix modulates the hallmarks of cancer
MW Pickup, JK Mouw, VM Weaver
EMBO reports 15 (12), 1243-1253, 2014
17962014
The roles of TGFβ in the tumour microenvironment
M Pickup, S Novitskiy, HL Moses
Nature Reviews Cancer 13 (11), 788-799, 2013
9912013
Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression
H Laklai, YA Miroshnikova, MW Pickup, EA Collisson, GE Kim, AS Barrett, ...
Nature medicine 22 (5), 497-505, 2016
5502016
Gr-1+ CD11b+ myeloid cells tip the balance of immune protection to tumor promotion in the premetastatic lung
HH Yan, M Pickup, Y Pang, AE Gorska, Z Li, A Chytil, Y Geng, JW Gray, ...
Cancer research 70 (15), 6139-6149, 2010
4122010
Tissue mechanics promote IDH1-dependent HIF1α–tenascin C feedback to regulate glioblastoma aggression
YA Miroshnikova, JK Mouw, JM Barnes, MW Pickup, JN Lakins, Y Kim, ...
Nature cell biology 18 (12), 1336-1345, 2016
3202016
Stromally derived lysyl oxidase promotes metastasis of transforming growth factor-β–deficient mouse mammary carcinomas
MW Pickup, H Laklai, I Acerbi, P Owens, AE Gorska, A Chytil, M Aakre, ...
Cancer research 73 (17), 5336-5346, 2013
2072013
From transformation to metastasis: deconstructing the extracellular matrix in breast cancer
S Kaushik, MW Pickup, VM Weaver
Cancer and Metastasis Reviews 35, 655-667, 2016
1662016
TGF-β receptor II loss promotes mammary carcinoma progression by Th17-dependent mechanisms
SV Novitskiy, MW Pickup, AE Gorska, P Owens, A Chytil, M Aakre, H Wu, ...
Cancer discovery 1 (5), 430-441, 2011
1552011
Integrin-mediated traction force enhances paxillin molecular associations and adhesion dynamics that increase the invasiveness of tumor cells into a three-dimensional …
AH Mekhdjian, FB Kai, MG Rubashkin, LS Prahl, LM Przybyla, ...
Molecular biology of the cell 28 (11), 1467-1488, 2017
1372017
Role of TGF-β signaling in generation of CD39+ CD73+ myeloid cells in tumors
SV Ryzhov, MW Pickup, A Chytil, AE Gorska, Q Zhang, P Owens, ...
The Journal of Immunology 193 (6), 3155-3164, 2014
1212014
Inhibition of BMP signaling suppresses metastasis in mammary cancer
P Owens, MW Pickup, SV Novitskiy, JM Giltnane, AE Gorska, CR Hopkins, ...
Oncogene 34 (19), 2437-2449, 2015
1152015
Disruption of bone morphogenetic protein receptor 2 (BMPR2) in mammary tumors promotes metastases through cell autonomous and paracrine mediators
P Owens, MW Pickup, SV Novitskiy, A Chytil, AE Gorska, ME Aakre, ...
Proceedings of the National Academy of Sciences 109 (8), 2814-2819, 2012
942012
ALCAM/CD166 Is a TGF-β–responsive marker and functional regulator of prostate cancer metastasis to bone
AG Hansen, SA Arnold, M Jiang, TD Palmer, T Ketova, A Merkel, ...
Cancer research 74 (5), 1404-1415, 2014
882014
Deletion of TGF-β signaling in myeloid cells enhances their anti-tumorigenic properties
SV Novitskiy, MW Pickup, A Chytil, D Polosukhina, P Owens, HL Moses
Journal of leukocyte biology 92 (3), 641-651, 2012
882012
Lack of transforming growth factor-β signaling promotes collective cancer cell invasion through tumor-stromal crosstalk
LA Matise, TD Palmer, WJ Ashby, A Nashabi, A Chytil, M Aakre, ...
Breast cancer research 14, 1-18, 2012
812012
A bulky glycocalyx fosters metastasis formation by promoting G1 cell cycle progression
EC Woods, FB Kai, JM Barnes, K Pedram, MW Pickup, MJ Hollander, ...
Elife 6, e25752, 2017
802017
TGF-β, bone morphogenetic protein, and activin signaling and the tumor microenvironment
MW Pickup, P Owens, HL Moses
Cold Spring Harbor perspectives in biology 9 (5), a022285, 2017
672017
Transforming growth factor beta receptor type III is a tumor promoter in mesenchymal-stem like triple negative breast cancer
B Jovanović, JS Beeler, MW Pickup, A Chytil, AE Gorska, WJ Ashby, ...
Breast Cancer Research 16, 1-14, 2014
642014
Stromal matrix metalloproteinase 2 regulates collagen expression and promotes the outgrowth of experimental metastases
AL Bates, MW Pickup, MA Hallett, EA Dozier, S Thomas, B Fingleton
The Journal of pathology 235 (5), 773-783, 2015
632015
Bone morphogenetic proteins stimulate mammary fibroblasts to promote mammary carcinoma cell invasion
P Owens, H Polikowsky, MW Pickup, AE Gorska, B Jovanovic, AK Shaw, ...
PloS one 8 (6), e67533, 2013
622013
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